HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethoxy)benzoyl chloride → N-(3-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)-3-(trifluoro methoxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethoxy)benzoyl chloride | HCID 522854 | — |
| Reactant | 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-2(1H)-one | HCID 46899946 | — |
| Product | N-(3-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)-3-(trifluoro methoxy)benzamide | HCID 44134091 | 20% |
Reaction Steps
Method G1 was used with 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-2(1H)-one and 3-trifluoromethoxybenzoyl chloride to afford the title compound as a white solid (35 mg, 20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912191B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-9f0e04fde0b14cd2bb5eb371f5268e1e |
| Source note | uspto-grants-2014_12 |