Dichloromethane → HCID 86701141, compound

Participants

Reaction Steps

A solution of compound (6) (0.050 g) and N,N-dimethylmethylene ammonium iodide (0.025 g) in methylene chloride (1 ml) was stirred overnight at room temperature. The reaction solution was partitioned between chloroform and water. The organic layer was neutralized with an aqueous sodium bicarbonate solution, then washed with brine, and then dried over anhydrous sodium sulfate. The solvent was distilled off, and the residue was then purified by neutral silica gel column chromatography (chloroform/methanol) to obtain compound (38) (0.053 g, 95%) as a pale yellow solid.

Provenance & Evidence