HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → 3-(3-Hydroxypropylsulfanyl)-dihydrofuran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-Mercaptopropanol | HCID 88211 | — |
| Reactant | 2(3H)-Furanone, 3-bromodihydro- | HCID 95463 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(3-Hydroxypropylsulfanyl)-dihydrofuran-2-one | HCID 66115662 | — |
Reaction Steps
To a solution of 3-mercapto-propan-1-ol (1685 μmol) in DMF (2 ml) were added DIEA (1.5 eq) and 3-bromo-dihydro-furan-2-one (1 eq). The reaction mixture was stirred at RT for 4 hours. The precipitate was filtered and the solvent was removed under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912209B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-eaabf590a4ad451382b8fbcaff73084c |
| Source note | uspto-grants-2014_12 |