Methyl triflate → 3-Methyl-1-(phenoxysulfonyl)-1H-imidazol-3-ium triflate

HRID 1403723Notes

Reaction equation

HRID 1403723 reaction equation
[N:1]1([S:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)(=[O:8])=[O:7])[CH:5]=[CH:4][N:3]=[CH:2]1.[O:16](C)[S:17]([C:20]([F:23])([F:22])[F:21])(=[O:19])=[O:18]>C(Cl)Cl>[O-:19][S:17]([C:20]([F:23])([F:22])[F:21])(=[O:18])=[O:16].[CH3:20][N+:3]1[CH:4]=[CH:5][N:1]([S:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)(=[O:8])=[O:7])[CH:2]=1

Participants

4

Reactant 2

HCID 9526Methyl triflateHCID 90409877Phenyl 1H-imidazole-1-sulfonate

Product 1

HCID 904096313-Methyl-1-(phenoxysulfonyl)-1H-imidazol-3-ium triflate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of phenyl 1H-imidazole-1-sulfonate (450 mg, 2.0 mmol) in DCM (15 mL) was treated with methyl triflate (390 mg, 2.4 mmol) at ambient temperature for 16 h. The solvent was removed and the residue was used for next step without further purification.

Workup

  1. customThe solvent was removed
  2. customthe residue was used for next step without further purification

Sources & evidence

ORD record
ord-6ee9a0128e08494d94700995c0f23e36
Source dataset
uspto-grants-2014_12
Patent number
US08912219B2

Reaction notes

Loading…