Aniline → HCID 131732175, compound

Participants

Reaction Steps

Sulfurisocyanatidic chloride (5.5 g, 39.05 mmol) was dropped into a solution of t-BuOH (2.89 g, 39.05 mmol) in DCM (100 mL) at 0° C., followed by addition of aniline (7.3 g, 78.10 mmol) and triethylamine (7.9 g, 78.10 mmol). The mixture was stirred at ambient temperature for 2 hours. The mixture was washed with water. The organic layer was dried over Na2SO4 and concentrated under reduced pressure to afford tent-butyl N-phenylsulfamoylcarbamate as white solid (9.5 g, 90%). LCMS (ESI): m/z=272.9 [M+H]+.

Provenance & Evidence