Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Phenylsulfonyl)aniline → (4-Benzenesulphonyl)phenyl-(6-iodo-7-fluoro-quinazolin-4-yl)-amine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Phenylsulfonyl)aniline | HCID 516666 | — |
| 반응물 | 4-Chloro-7-fluoro-6-iodoquinazoline | HCID 21952006 | — |
| 생성물 | (4-Benzenesulphonyl)phenyl-(6-iodo-7-fluoro-quinazolin-4-yl)-amine hydrochloride | HCID 68594451 | — |
반응 단계
Prepared according to Procedure A from 4-(benzenesulphonyl)phenylamine and 4-chloro-6-iodo-7-fluoroquinazoline. 1H NMR (400 MHz, DMSO-d6) δ: 10.89 (s, 1H), 9.3 (d, 1H), 8.79 (s, 1H), 8.07 (d, 2H), 8.0 (d, 2H), 7.94 (d, 2H), 7.67 (m, 2H), 7.61 (m, 2H). ESI-MS m/z 504 (M−1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08912205B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-b1c4e43b59d14596a1b701abbfcf2b63 |
| 출처 메모 | uspto-grants-2014_12 |