1-Chloro-4-(chloromethyl)benzene → HCID 50997041, compound
Reaction equation
C(OC1C=CC(F)=C2C=1C(CCN(C)C)=CN2C)C1C=CC=CC=1.[CH3:25][N:26]([CH3:42])[CH2:27][CH2:28][C:29]1[C:37]2[C:36]([OH:38])=[CH:35][C:34]([F:39])=[CH:33][C:32]=2[N:31]([CH2:40][CH3:41])[CH:30]=1.[Cl:43][C:44]1[CH:49]=[CH:48][C:47]([CH2:50]Cl)=[CH:46][CH:45]=1>>[Cl:43][C:44]1[CH:49]=[CH:48][C:47]([CH2:50][O:38][C:36]2[CH:35]=[C:34]([F:39])[CH:33]=[C:32]3[C:37]=2[C:29]([CH2:28][CH2:27][N:26]([CH3:25])[CH3:42])=[CH:30][N:31]3[CH2:40][CH3:41])=[CH:46][CH:45]=1Participants
4
Procedure
Following the procedure (step 7, scheme 1) used to prepare compound 1-8c, compound 1-9b and 1-chloro-4-(chloromethyl)benzene were used as starting material to obtain compound 1-10b.
Sources & evidence
- ORD record
- ord-f9e3afbc54bd4174bd36fd8ef923cd7f
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912220B2
Reaction notes
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