HCID 11701439, compound → HCID 50997219, compound

HRID 1404079Notes

Reaction equation

HRID 1404079 reaction equation
CN(C)CCC1C2C(O)=CC=C(F)C=2N(C)C=1.[CH2:18]([N:20]1[C:28]2[C:23](=[C:24]([O:30][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=3[N+:37]([O-])=O)[CH:25]=[CH:26][C:27]=2[F:29])[C:22]([CH2:40][CH2:41][N:42]([CH3:44])[CH3:43])=[CH:21]1)[CH3:19]>[Pd]>[CH3:44][N:42]([CH3:43])[CH2:41][CH2:40][C:22]1[C:23]2[C:28](=[C:27]([F:29])[CH:26]=[CH:25][C:24]=2[O:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=2[NH2:37])[N:20]([CH2:18][CH3:19])[CH:21]=1

Participants

4

Reactant 2

HCID 11701439HCID 11701439, compoundHCID 50997220HCID 50997220, compound

Product 1

HCID 50997219HCID 50997219, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst2×

Procedure

Following the procedure (step 8, scheme 1) used to prepare compound 1-9c, compound 2-2 was used as starting material, using Pd/C (10%) as source of Pd to obtain compound 2-3.

Sources & evidence

ORD record
ord-1f09c091394c47a7ae635d7f26fb5052
Source dataset
uspto-grants-2014_12
Patent number
US08912220B2

Reaction notes

Loading…