HCID 58303866, compound → HCID 58303872, compound

Participants

Reaction Steps

Following the procedure (step 6, scheme 17) used to prepare compound 17-7, compound 20-3 was used as starting material, giving compound 20-4 in 68% yield as a white solid, which was converted to the hydrochloride salt. 1H NMR (DMSO-d6, 300 MHz) δ (ppm) (HCl salt): 9.25 (br, 2H), 7.54-7.57 (m, 2H), 7.42-7.44 (m, 3H), 7.16 (s, 1H), 6.82 (dd, J=12.4, 8.5 Hz, 1H), 6.35 (dd, J=8.5, 2.7 Hz, 1H), 4.21 (q, J=7.1 Hz, 2H), 4.17 (s, 2H), 3.75 (s, 3H), 3.12 (br, 4H), 1.32 (t, J=7.1 Hz, 3H). LRMS: calc 326.2 found 327.2 [MH]+.

Provenance & Evidence