HCID 58303866, compound → HCID 50995812, compound

Participants

Reaction Steps

Following the procedure (step 6, scheme 17) used to prepare compound 17-7, compound 22-4 was used as starting material, giving compound 22-5 in 47% yield as a colorless oil, which was converted to the hydrochloride salt. 1H NMR (DMSO-d6, 300 MHz) δ (ppm) (HCl salt): 8.63 (br, 2H), 7.57-7.60 (m, 2H), 7.45 (t, J=7.4 Hz, 2H), 7.30-7.36 (m, 1H), 7.23 (s, 1H), 6.93 (d, J=12.9 Hz, 1H), 3.90 (d, J=1.9 Hz, 3H), 3.36 (s, 3H), 3.16-3.21 (m, 2H), 3.06-3.11 (m, 2H), 2.59 (s, 3H). LRMS: calc 312.2 found 313.1 [MH]+.

Provenance & Evidence