Methyl iodide → HCID 58303914, compound

Participants

Reaction Steps

To a solution of 30-10 (2 g, 7 mmol) in acetone (40 mL) was added K2CO3 (3 g, 21 mmol) and MeI (1.2 g, 8.4 mmol). The reaction mixture was refluxed overnight before it was cooled to room temperature. The solid was filtered off and the filtrate was evaporated to give the crude product, which was purified on silica gel column chromatography eluting with hexane/ethyl acetate (1:5) to afford 30-11 (1.4 g, 67%) as a yellow solid. LRMS: calc 299.1 and found: 300.1 [M+1].

Provenance & Evidence