Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1404146Generated: November 2, 2026

2-(1-ethyl-4-methoxy-6-phenyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide → 2-(dimethylamino)-1-(1-ethyl-4-methoxy-6-phenyl-1H-indol-3-yl)ethanol

https://huagongshe.com/reaction/1404146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-ethyl-4-methoxy-6-phenyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamideHCID 58304012—
Reactant2-(4-Benzyloxy-5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamineHCID 66927088—
Product2-(dimethylamino)-1-(1-ethyl-4-methoxy-6-phenyl-1H-indol-3-yl)ethanolHCID 5830403068%

Reaction Steps

Following the procedure (step 6, scheme 1) used to prepare compound 1-7a, compound 36-4 gave compound 36-5 (68%), which was taken on to the final step without further purification. LCMS: calc 338.2 and found: 313.1 [MH−water]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912220B2
Source datasetuspto-grants-2014_12
ORD IDord-550d78428a014f02ad9db0637996836d
Source noteuspto-grants-2014_12