HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(benzyloxy)-7-bromo-5-fluoro-1-methyl-1H-indole → 6-bromo-7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(benzyloxy)-7-bromo-5-fluoro-1-methyl-1H-indole | HCID 58303958 | — |
| Reactant | 6-bromo-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indole | HCID 66927131 | — |
| Product | 6-bromo-7-propyl-3,7-dihydro-2H-[1,4]dioxino[2,3-e]indole | HCID 66927219 | 90% |
Reaction Steps
Following the procedure (step 2, scheme 33) used to prepare compound 33-3, compound 40-2 gave compound 40-3 in 90% yield as a yellow solid. LCMS: calc 295.0 found 296.0 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912220B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-2768aac443b44f7bbf9278d51641dd9e |
| Source note | uspto-grants-2014_12 |