(4-Bromophenyl)boronic acid → HCID 90406842, compound

HRID 1404175Notes

Reaction equation

HRID 1404175 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([O:8][CH3:9])=O.[Br:10][C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1.[CH3:20][C:21]1[C:26](C)=[C:25](O)[CH:24]=[CH:23][C:22]=1[CH2:29][CH2:30][C:31]([O:33]CC)=[O:32]>>[Br:10][C:11]1[CH:16]=[CH:15][C:14]([N:1]2[CH:5]=[CH:4][CH:3]=[C:2]2[CH2:6][O:8][C:9]2[CH:24]=[CH:23][C:22]([CH2:29][CH2:30][C:31]([OH:33])=[O:32])=[C:21]([CH3:20])[C:26]=2[CH3:25])=[CH:13][CH:12]=1

Participants

4

Reactant 3

HCID 79599(4-Bromophenyl)boronic acidHCID 136930Methyl pyrrole-2-carboxylateHCID 58566491Ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoate

Product 1

HCID 90406842HCID 90406842, compound

Procedure

The title compound was prepared by reacting methyl 1H-pyrrole-2-carboxylate with 4-bromophenylboronic acid according to the procedures of Example 1, Steps C and D, then reacting the resulting product with ethyl 3-(2,3-dimethyl-4-hydroxyphenyl)propanoate according to the procedures described in Example 1, Steps E and F.

Sources & evidence

ORD record
ord-95c0b6c4fda8499396f3651eaffadbed
Source dataset
uspto-grants-2014_12
Patent number
US08912227B1

Reaction notes

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