Methanol → HCID 117734585, compound

Participants

Reaction Steps

To a solution of the product prepared in Example 1 (1.10 g, 2.39 mmol, 1 eq) in methanol (20 mL) at room temperature was added thionyl chloride (0.027 mL, 0.36 mmol, 0.15 eq). After stirring the resulting mixture for 3 hrs, the solution was concentrated. Purification of the mixture by chromatography (40 g) eluting with 2 to 10% ethyl acetate//heptane yielded the title compound.

Provenance & Evidence