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HRID1404326

反应详情

EQUATION

反应方程式

HRID 1404326 的结构方程式

REACTANTS

反应物

2
反应SMILES：ClB(Cl)Cl
HCID25135

Boron trichloride

BCl3

反应SMILES：COc1c(C[C@H](NC(=O)C[C@H]2CC[C@H](NC(=O)OC(C)(C)C)CC2)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)O
HCID178491876

未命名化合物

PRODUCTS

产物

1
反应SMILES：N[C@H]1CC[C@H](CC(=O)N[C@H]2Cc3cccc(C(=O)O)c3OB2O)CC1
HCID178511528

未命名化合物

PROCEDURE

实验过程

Prepared from 3-((2R)-2-(2-(trans-4-(tert-butoxycarbonylamino)cyclohexyl)acetamido)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)ethyl)-2-methoxybenzoic acid and BCl3 following the procedure described in Step 2 of Example 1. The crude product was purified by reverse phase preparative HPLC and dried using lyophilization. ESI-MS m/z 347 (MH)+.

WORKUP

后处理

  1. customThe crude product was purified by reverse phase preparative HPLC
  2. customdried