Potassium Carbonate → HCID 86722963, compound

Participants

Reaction Steps

To a suspension of trans-N-Boc-1,4-diaminocyclohexane (0.256 g, 1.19 mmol) and potassium carbonate (0.663 g, 4.80 mmol) in acetonitrile (15 mL) and DMF (5 mL) was added benzyl bromoacetate (0.21 mL, 1.33 mmol) under argon and the reaction was stirred at RT for 19 hr. The reaction was diluted with ethyl acetate and washed with sat. NaHCO3 and brine. The organic layer was dried over Na2SO4, filtered, and concentrated. The crude product was carried forward without purification. ESI-MS m/z 363 (MH)+.

Provenance & Evidence