HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ac-430 → HCID 178419998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ac-430 | HCID 46892373 | — |
| Reactant | (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol | HCID 56833308 | — |
| Product | HCID 178419998 | HCID 178419998 | — |
Reaction Steps
or an isotopic variant thereof; or pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof. (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol was determined to be the (−) isomer of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol by optical rotation analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912324B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-9f7c51295c4e4bd9b998930d66e06c92 |
| Source note | uspto-grants-2014_12 |