Succinimide → HCID 67290424, compound
Reaction equation
[NH:1]1[C:5](=O)[CH2:4][CH2:3][C:2]1=[O:7].Br[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1>>[N:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[CH2:9][CH:5]1[NH:1][C:2](=[O:7])[CH2:3][CH2:4]1Participants
3
Procedure
5-(Pyridin-2-ylmethyl)pyrrolidin-2-one is synthesized from pyrrolidine-2,5-dione and 2-(bromomethyl)pyridine according to S. Lebrun et al. (Tetrahedron Asymmetry 2003, 14, 2625-2632).
Sources & evidence
- ORD record
- ord-9df4b97a79204b6a8089a9b9528187b8
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912329B2
Reaction notes
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