(1-Benzothiophen-3-yl)boronic acid → 6-(1-benzothiophen-3-yl)-1-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine

HRID 1404575Notes

Reaction equation

HRID 1404575 reaction equation
[CH2:1]([O:8][N:9]1[C:17]2[C:12](=[N:13][CH:14]=[C:15](Br)[CH:16]=2)[CH:11]=[CH:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:19]1[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[C:21](B(O)O)=[CH:20]1>>[S:19]1[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[C:21]([C:15]2[CH:16]=[C:17]3[N:9]([O:8][CH2:1][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)[CH:10]=[CH:11][C:12]3=[N:13][CH:14]=2)=[CH:20]1

Participants

3

Reactant 2

HCID 2776344(1-Benzothiophen-3-yl)boronic acidHCID 674577271-(benzyloxy)-6-bromo-1H-pyrrolo[3,2-b]pyridine

Product 1

HCID 585322646-(1-benzothiophen-3-yl)-1-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine

Procedure

The entitled compound was prepared from 1-(benzyloxy)-6-bromo-1H-pyrrolo[3,2-b]pyridine and 1-benzothiophen-3-ylboronic acid according to the procedure described in Example 1.

Sources & evidence

ORD record
ord-bde8fc945cb2403d9e0a91c329ab2a6f
Source dataset
uspto-grants-2014_12
Patent number
US08912330B2

Reaction notes

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