1-Methyl-1H-indole-5-boronic acid → 1-(benzyloxy)-6-(1-methyl-1H-indol-5-yl)-1H-pyrrolo[3,2-b]pyridine

HRID 1404576Notes

Reaction equation

HRID 1404576 reaction equation
[CH2:1]([O:8][N:9]1[C:17]2[C:12](=[N:13][CH:14]=[C:15](Br)[CH:16]=2)[CH:11]=[CH:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][N:20]1[C:28]2[C:23](=[CH:24][C:25](B(O)O)=[CH:26][CH:27]=2)[CH:22]=[CH:21]1>>[CH2:1]([O:8][N:9]1[C:17]2[C:12](=[N:13][CH:14]=[C:15]([C:25]3[CH:24]=[C:23]4[C:28](=[CH:27][CH:26]=3)[N:20]([CH3:19])[CH:21]=[CH:22]4)[CH:16]=2)[CH:11]=[CH:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27598671-Methyl-1H-indole-5-boronic acidHCID 674577271-(benzyloxy)-6-bromo-1H-pyrrolo[3,2-b]pyridine

Product 1

HCID 585322561-(benzyloxy)-6-(1-methyl-1H-indol-5-yl)-1H-pyrrolo[3,2-b]pyridine

Procedure

The entitled compound was prepared from 1-(benzyloxy)-6-bromo-1H-pyrrolo[3,2-b]pyridine and (1-methyl-1H-indol-5-yl)boronic acid according to the procedure described in Example 1.

Sources & evidence

ORD record
ord-822ef6d063bc40c98bad287be627f7c1
Source dataset
uspto-grants-2014_12
Patent number
US08912330B2

Reaction notes

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