1-Methyl-1H-indole-5-boronic acid → HCID 58532294, compound

HRID 1404589Notes

Reaction equation

HRID 1404589 reaction equation
Br[C:2]1[CH:3]=[C:4]2[N:10]([O:11][CH:12]([C:14]3[C:19]([Cl:20])=[CH:18][CH:17]=[C:16]([F:21])[C:15]=3[Cl:22])[CH3:13])[CH:9]=[CH:8][C:5]2=[N:6][CH:7]=1.[CH3:23][N:24]1[C:32]2[C:27](=[CH:28][C:29](B(O)O)=[CH:30][CH:31]=2)[CH:26]=[CH:25]1>>[Cl:22][C:15]1[C:16]([F:21])=[CH:17][CH:18]=[C:19]([Cl:20])[C:14]=1[CH:12]([O:11][N:10]1[C:4]2[C:5](=[N:6][CH:7]=[C:2]([C:29]3[CH:28]=[C:27]4[C:32](=[CH:31][CH:30]=3)[N:24]([CH3:23])[CH:25]=[CH:26]4)[CH:3]=2)[CH:8]=[CH:9]1)[CH3:13]

Participants

3

Reactant 2

HCID 27598671-Methyl-1H-indole-5-boronic acidHCID 674584186-bromo-1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridine

Product 1

HCID 58532294HCID 58532294, compound

Procedure

The entitled compound was prepared from 6-bromo-1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridine and (1-methyl-1H-indol-5-yl)boronic acid according to the procedure described in example 4.

Sources & evidence

ORD record
ord-c27fd6194ff843e4a1b37c4271ef4df3
Source dataset
uspto-grants-2014_12
Patent number
US08912330B2

Reaction notes

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