Hydrochloric Acid → HCID 58532497, compound

Participants

Reaction Steps

The entitled compound was prepared from 6-bromo-1-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1H-pyrrolo[3,2-b]pyridine and tert-butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate according to the procedure described in example 4. The resulting compound (BOC protected compound) was dissolved in methanol and was treated with HCl (4.0M solution in dioxane,) at room temperature for 30 min. Solvents were evaporated and the residue was dissolved in DCM and treated with Na2CO3/NaHCO3 and drops of water. The solution was then purified to give the entitled compound.

Provenance & Evidence