tert-butyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate → tert-butyl 4-{4-[1-(benzylamino)-1H-pyrrolo[3,2-b]pyridin-6-yl]-1H-pyrazol-1-yl}piperidine-1-carboxylate

Participants

Role	Name	HCID	Charge
Reactant	tert-butyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate	HCID 45480279	—
Reactant	N-benzyl-6-bromo-1H-pyrrolo[3,2-b]pyridine-1-amine	HCID 67459766	—
Product	tert-butyl 4-{4-[1-(benzylamino)-1H-pyrrolo[3,2-b]pyridin-6-yl]-1H-pyrazol-1-yl}piperidine-1-carboxylate	HCID 67458095	—

Reaction Steps

This intermediate was prepared using Suzuki coupling reaction of N-benzyl-6-bromo-1H-pyrrolo[3,2-b]pyridine-1-amine and tert-butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate as described in example 1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08912330B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-82fb6c73eeee4112b051daf12450cdde
Source note	uspto-grants-2014_12