Toluene → Benzophenone

Participants

Reaction Steps

The above compound of the formula (32), 13.7 g (142.8 mmol) of sodium-t-butoxide, 0.7 g (1.3 mmol) of bis(dibenzylideneacetone)palladium, 1.75 g (1.3 mmol) of 1-dicyclohexylphosphino-2-di-t-butylphosphinoethyl ferrocene and 17.9 g (129.8 mmol) of 2,6-dimethylthiobenzene were dissolved in 400 ml of toluene in an argon atmosphere and refluxed for 3 hours. After a reaction, the reaction solution was washed with water, the solvent was removed, and the obtained product was purified by column chromatography to obtain a benzophenone derivative represented by the following formula (33) as 41.1 g (118.1 mmol, yield of 91%) of a white solid.

Provenance & Evidence