反应详情

A mixed solution of 4.1 g of pyrene, 2 g of t-butyl chloride and 33 ml of dichloromethane was cooled to 0° C. under a nitrogen stream, and 2.7 g of aluminum chloride was added. After this mixed solution was stirred at room temperature for 3 hours, 30 ml of water was added, and this was extracted with 30 ml of dichloromethane. The organic layer was washed with 20 ml of water two times, dried with magnesium sulfate, and evaporated. This was purified by silica gel column chromatography, and vacuum-dried to obtain 3 g (content 65%) of 2-t-butylpyrene.

1. additionwas added
2. extractionthis was extracted with 30 ml of dichloromethane
3. washThe organic layer was washed with 20 ml of water two times
4. dry with materialdried with magnesium sulfate
5. customevaporated
6. customThis was purified by silica gel column chromatography
7. customvacuum-dried