反应详情

Then, a mixed solution of 106.9 g of 1-bromo-7-t-butylpyrene, 54.5 g of 4-chlorophenylboronic acid, 0.223 g of bis(triphenylphosphine)dichloropalladium, 350 ml of an aqueous 2M sodium carbonate solution and 1586 ml of 1,2-dimethoxyethane was heated and stirred for about 5 hours under a nitrogen stream and under refluxing. After the mixture was cooled to room temperature, 640 ml of water was added, and this was extracted with 1170 ml of toluene. The organic layer was washed with 640 ml of water two times, dried with magnesium sulfate, and evaporated, 270 ml of toluene and 1350 ml of methanol were added, and the mixture was stirred for about 2 hours, and filtered. After the resultant was vacuum dried, 105.16 g of 7-t-butyl-1-(4-chlorophenyl)pyrene was obtained.

1. temperatureunder refluxing
2. extractionthis was extracted with 1170 ml of toluene
3. washThe organic layer was washed with 640 ml of water two times
4. dry with materialdried with magnesium sulfate
5. customevaporated
6. addition270 ml of toluene and 1350 ml of methanol were added
7. stirringthe mixture was stirred for about 2 hours
8. filtrationfiltered
9. customdried