2-Chloro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one → 2-(6-Chloro-benzothiazol-2-ylsulfanyl)-1-(3,4-dihydro-2H-quinolin-1-yl)-ethanone

Participants

Reaction Steps

The title compound was synthesized according to General Procedure A using compound 4 as the electrophile and 6-chlorobenzo[d]thiazole-2-thiol as the nucleophile to yield 25 as a white solid (73%): MS m/z: 375 (M+H)+. Anal. Calcd. For, C18H15ClN2OS2: C, 57.67; H, 4.03; N, 7.47; S, 17.11; Cl, 9.46. Found: C, 57.50; H, 4.05; N, 7.48; S, 16.86; Cl, 9.74.

Provenance & Evidence