Quinoline, 1,2,3,4-tetrahydro-6-methoxy- → HCID 41199566, compound

HRID 1404927Notes

Reaction equation

HRID 1404927 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([OH:14])=O.[CH3:15][O:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[NH:23][CH2:22][CH2:21][CH2:20]2>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([N:23]1[C:24]2[C:19](=[CH:18][C:17]([O:16][CH3:15])=[CH:26][CH:25]=2)[CH2:20][CH2:21][CH2:22]1)=[O:14]

Participants

3

Reactant 2

HCID 67113Quinoline, 1,2,3,4-tetrahydro-6-methoxy-HCID 805252-(2-Benzothiazolylthio)acetic acid

Product 1

HCID 41199566HCID 41199566, compound

Procedure

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 6-methoxy-1,2,3,4-tetrahydroquinoline to yield 39 (245 mg, 1.5 mmol). MS (APCI): m/z 371 [M+H]+. Anal. Calcd. for C19H18N2O2S2: C, 61.60; H, 4.90; N, 7.56. Found: C, 61.49; H, 4.87; N, 7.59.

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-89dd3d6bc69748af8f42d8c479ba51b5
Source dataset
uspto-grants-2014_12
Patent number
US08916550B2

Reaction notes

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