2-(2-Benzothiazolylthio)acetic acid → HCID 32612276, compound

HRID 1404931Notes

Reaction equation

HRID 1404931 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([OH:14])=O.[O:15]1[CH2:20][CH2:19][NH:18][C:17]2[CH:21]=[CH:22][CH:23]=[CH:24][C:16]1=2>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([N:18]1[C:17]2[CH:21]=[CH:22][CH:23]=[CH:24][C:16]=2[O:15][CH2:20][CH2:19]1)=[O:14]

Participants

3

Reactant 2

HCID 805252-(2-Benzothiazolylthio)acetic acidHCID 5850963,4-Dihydro-2H-1,4-benzoxazine

Product 1

HCID 32612276HCID 32612276, compoundYield 78%

Procedure

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 3,4-dihydro-2H-benzo[b][1,4]oxazine to yield 44 as a white solid (78%): MS m/z: 343 (M+H)+. Anal. Calcd. For, C17H14N2O2S2: C, 59.63; H, 4.12; N, 8.18; S, 18.73. Found: C, 59.73; H, 4.17; N, 8.18; S, 18.76.

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-f44017743b154c1898cfc97cef1315e2
Source dataset
uspto-grants-2014_12
Patent number
US08916550B2

Reaction notes

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