1,2,3,4-Tetrahydroquinoline → HCID 42886374, compound

HRID 1404934Notes

Reaction equation

HRID 1404934 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]([CH3:15])[C:12]([OH:14])=O.[NH:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]([CH3:15])[C:12]([N:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1)=[O:14]

Participants

3

Reactant 2

HCID 694601,2,3,4-TetrahydroquinolineHCID 29022242-[(1,3-Benzothiazol-2-yl)sulfanyl]propanoic acid

Product 1

HCID 42886374HCID 42886374, compoundYield 34%

Procedure

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)propanoic acid and 1,2,3,4-tetrahydroquinoline to yield 47 as a yellow oil (34%): MS m/z: 355 (M+H)+. Anal. Calcd. For, C19H18N2OS2: C, 64.38; H, 5.12; N, 7.90; S, 18.09. Found: C, 64.38; H, 5.26; N, 7.97; S, 18.08.

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-2bfd4baf31df4b88831c2083c3a45950
Source dataset
uspto-grants-2014_12
Patent number
US08916550B2

Reaction notes

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