1,2,3,4-Tetrahydroquinoline → HCID 59467912, compound

HRID 1404943Notes

Reaction equation

HRID 1404943 reaction equation
[NH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[S:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]=[C:12]1[O:20][CH2:21][C:22](O)=[O:23]>>[S:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]=[C:12]1[O:20][CH2:21][C:22]([N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1)=[O:23]

Participants

3

Reactant 2

HCID 694601,2,3,4-TetrahydroquinolineHCID 2435072-(Benzo[d]thiazol-2-yloxy)acetic acid

Product 1

HCID 59467912HCID 59467912, compoundYield 28%

Procedure

Compound 62 was synthesized according to General Procedure B using compound 3 and compound 61 to yield 62 (183 mg, 28%): MS (APCI): m/z 325 [M+H]+. Anal. Calcd. for C18H16N2O2S: C, 66.64; H, 4.97; N, 8.64. Found: C, 66.88; H, 4.94; N, 8.60.

Workup

  1. customCompound 62 was synthesized

Sources & evidence

ORD record
ord-3e1b7b6be2de49b7ac816c795b20e974
Source dataset
uspto-grants-2014_12
Patent number
US08916550B2

Reaction notes

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