HCID 67959399, compound → 8-Cyclopropyl-2-methyl-2,3,4,5-tetrahydrothieno[2,3-f][1,4]oxazepine

HRID 1404974Notes

Reaction equation

HRID 1404974 reaction equation
[CH:1]1([C:4]2[C:13]3[O:12][CH:11]([CH3:14])[CH2:10][N:9](C(OC(C)(C)C)=O)[CH2:8][C:7]=3[S:6][CH:5]=2)[CH2:3][CH2:2]1>C(OCC)(=O)C.Cl>[CH:1]1([C:4]2[C:13]3[O:12][CH:11]([CH3:14])[CH2:10][NH:9][CH2:8][C:7]=3[S:6][CH:5]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 67959399HCID 67959399, compound

Product 1

HCID 679591998-Cyclopropyl-2-methyl-2,3,4,5-tetrahydrothieno[2,3-f][1,4]oxazepine

Reagents, catalysts & solvents 1

HCID 21866389Hydrogen chloride-ethyl acetateSolvent

Procedure

tert-Butyl 8-cyclopropyl-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepine-4(5H)-carboxylate (254 mg) was stirred in 4N hydrogen chloride-ethyl acetate solution (5 ml,) for 20 min.

Sources & evidence

ORD record
ord-a6972425ded24818b76e1f884f2e4b71
Source dataset
uspto-grants-2014_12
Patent number
US08916549B2

Reaction notes

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