HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → 4-Chloro-6-ethyl-5-iodo-pyrimidin-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 2-Amino-4-chloro-6-ethylpyrimidine | HCID 22324304 | — |
| Product | 4-Chloro-6-ethyl-5-iodo-pyrimidin-2-ylamine | HCID 58513296 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP1 starting from 2.5 g (16 mmol) 4-chloro-6-ethyl-pyrimidin-2-ylamine and 3.7 g (16 mmol) NIS. Yield after precipitation from the reaction mixture: 3.83 g (85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916548B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-029a2c9929184d88a85d2d5999157e0b |
| Source note | uspto-grants-2014_12 |