HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14051Generated: October 30, 2026
Lithium Hydroxide → HCID 21085837, compound
https://huagongshe.com/reaction/14051
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 21086188 | HCID 21086188 | — |
| Solvent | Methanol tetrahydrofuran water | HCID 21892291 | — |
| Product | HCID 21085837 | HCID 21085837 | — |
Reaction Steps
Methyl 3-methyl-5-(3-thienyl)benzoate (257 mg, 1.1 mmol) is treated with lithium hydroxide (186 mg, 4.4 mmol) in tetrahydrofuran/methanol/water (8 ml, 2:1:1) and the mixture is stirred for 2 hours at 20-25 degrees C. The mixture is acidified and concentrated to give the title compound, MS [M+H]+=217.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07727997B2 |
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| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-3533390d04bb467d907ad8a87f0cefa4 |
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| Source note | uspto-grants-2010_06 |
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