4-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine → HCID 66576358, compound

HRID 1405181Notes

Reaction equation

HRID 1405181 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=2)[N:3]=1.[O:20]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][C:28]=2B(O)O)[CH2:23][CH2:22][CH2:21]1>>[O:20]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][C:28]=2[C:2]2[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=3)[N:3]=2)[CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 219563434-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amineHCID 534384643,4-Dihydro-2H-1-benzopyran-8-ylboronic acid

Product 1

HCID 66576358HCID 66576358, compound

Procedure

Example 12 was prepared under similar conditions as described in the preparation of Example 1 using crude 4-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine and 3,4-dihydro-2H-chromen-8-ylboronic acid (Parkway Scientific LLC).

Workup

  1. customExample 12 was prepared under similar conditions

Sources & evidence

ORD record
ord-fa6404688ed84cca8906520c15813748
Source dataset
uspto-grants-2014_12
Patent number
US08916557B2

Reaction notes

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