(2-Methoxypyridin-3-yl)boronic acid → HCID 66576434, compound

HRID 1405187Notes

Reaction equation

HRID 1405187 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=2)[N:3]=1.[CH3:20][O:21][C:22]1[C:27](B(O)O)=[CH:26][CH:25]=[CH:24][N:23]=1>>[CH3:20][O:21][C:22]1[C:27]([C:2]2[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=3)[N:3]=2)=[CH:26][CH:25]=[CH:24][N:23]=1

Participants

3

Reactant 2

HCID 2762709(2-Methoxypyridin-3-yl)boronic acidHCID 219563434-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine

Product 1

HCID 66576434HCID 66576434, compound

Procedure

Example 20 was prepared under similar conditions as described in the preparation of Example 1 using crude 4-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine and (2-methoxypyridin-3-yl)boronic acid (Aldrich Chemical Company Inc.). The batch was purified by preparative HPLC.

Workup

  1. customExample 20 was prepared under similar conditions
  2. customThe batch was purified by preparative HPLC

Sources & evidence

ORD record
ord-5658228b9f4841f59c94d5a638a5500b
Source dataset
uspto-grants-2014_12
Patent number
US08916557B2

Reaction notes

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