alpha-Chloro-m-nitrotoluene → HCID 4322234, compound

Participants

Reaction Steps

A solution of 3-nitrobenzyl chloride (10.0 g) in ethanol (120 mL) was cooled to 0° C., treated with sodium thiophenolate (9.1 g, 90%) in 3 portions, while the temperature was slowly increased to room temperature the mixture was stirred for 18 hours. The reaction mixture was then concentrated in vacuo, treated with diethyl ether (350 mL), washed with water (2×150 mL) and brine (100 mL), dried with sodium sulfate and evaporated to dryness. The title compound (14.6 g) was thus obtained and used without further purification.

Provenance & Evidence