HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → 4-[4-Fluoro-2-(2-methoxyethoxy)phenyl]-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine | HCID 70976524 | — |
| Product | 4-[4-Fluoro-2-(2-methoxyethoxy)phenyl]-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine | HCID 66576839 | — |
Reaction Steps
Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (50 mg; 0.19 mmol), intermediate 42.1, and 2-methoxyethanol (42 μl; 0.515 mmol), example 50 was prepared analogously to the procedure for the preparation of example 42.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916557B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8328016c14ef43a79bbe13a9d5d09f00 |
| Source note | uspto-grants-2014_12 |