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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1405239Generated: October 30, 2026

3-(Trifluoromethyl)benzylic alcohol → HCID 66575811, compound

https://huagongshe.com/reaction/1405239

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzylic alcoholHCID 67681—
Reactant4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amineHCID 70976524—
ProductHCID 66575811HCID 66575811—

Reaction Steps

Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (70 mg; 0.184 mmol), intermediate 42.1, and 3-(trifluoromethyl)benzyl alcohol (132 mg; 0.736 mmol), example 69 was prepared analogously to the procedure for the preparation of example 42.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916557B2
Source datasetuspto-grants-2014_12
ORD IDord-9c369116a1fd406eb9dd7ed304e960bb
Source noteuspto-grants-2014_12