Triethylamine → 4,4,5,5-tetramethyl-2-{(E)-2-[4-(1-methylethyl)phenyl]ethenyl}-1,3,2-dioxaborolane

참여 물질

역할	이름	HCID	투입량
반응물	Triethylamine	HCID 8471	—
반응물	1-Ethynyl-4-(1-methylethyl)benzene	HCID 637501	—
반응물	4,4,5,5-Tetramethyl[1,3,2]dioxaborolane	HCID 2734768	—
촉매	Bis(cyclopenta-1,3-diene);hydride;zirconium(2+);chloride	HCID 131718033	—
용매	Hexane	HCID 8058	—
생성물	4,4,5,5-tetramethyl-2-{(E)-2-[4-(1-methylethyl)phenyl]ethenyl}-1,3,2-dioxaborolane	HCID 68280923	91.3%

반응 조건

온도	80 °C

반응 단계

A mixture of triethylamine (246 mg), 1-ethynyl-4-isopropylbenzene (3500 mg), 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (3417 mg) and zirconocene chloride hydride (626 mg) was stirred at 80° C. overnight. To the reaction mixture was added hexane, and the mixture was filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (6030 mg) as a yellow solid.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08916551B2
출처 데이터셋	uspto-grants-2014_12
ORD ID	ord-ad30884369834e00b5091e8dfa87c5ee
출처 메모	uspto-grants-2014_12