Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1405811생성일: 2026년 10월 25일
Hydrochloric Acid → 4-(2,2-Dioxido-3,4,6,7,8,9-hexahydropyrido[2,1-c][1,2,4]thiadiazin-9-yl)phenol
https://huagongshe.com/reaction/1405811
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 9-(4-((Tert-butyl(dimethyl)silyl)oxy)phenyl)-3,4,6,7,8,9-hexahydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide | HCID 66747996 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-(2,2-Dioxido-3,4,6,7,8,9-hexahydropyrido[2,1-c][1,2,4]thiadiazin-9-yl)phenol | HCID 66747720 | 101.2% |
반응 단계
A mixture of 9-(4-((tert-butyldimethylsilyl)oxy)phenyl)-3,4,6,7,8,9-hexahydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide (6.97 g) and 6 M HCl aq. (10.0 mL) in AcOH (100 mL) was stirred at 60° C. for 2 hr. After cooling to room temperature, the solvent was removed in vacuo. The residual solid was recrystallized from MeOH—IPE to give the title compound (5.01 g) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08916551B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_12 |
|---|
| ORD ID | ord-3e4145b7648f45f89c00031ac7b36518 |
|---|
| 출처 메모 | uspto-grants-2014_12 |
|---|
