HCID 68358107, compound → HCID 68295422, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of ethyl (7E)-7-[(dimethylamino)methylidene]-1-methyl-8-oxo-1,4,5,6,7,8-hexahydrocyclohepta[c]pyrazole-3-carboxylate 1.72 g (5.92 mmol) in 20 mL of DMF N-(4-Bromo-2-methoxy-phenyl)-guanidine 1.60 g (6.511 mmol) was added. The mixture was stirred at 120° C. for 4 h. The resulting mixture was cooled at room temperature and dried to dryness. The crude solid was purified by flash chromatography on silica gel (eluant: AcOEt/hexane 4/6) to afford 2.30 g (82% yield) of the title compound as a yellow solid.

Provenance & Evidence