Benzylamine → HCID 86701831, compound

Participants

Reaction Steps

A suspension of potassium 9-[(4-bromo-2-methoxyphenyl)amino]-2-methyl-2,4,5,6-tetrahydropyrazolo[4′,3′:6,7]cyclohepta[1,2-d]pyrimidine-3-carboxylic acid (0.050 g, 0.110 mmol) in anhydrous DMF (5.0 mL) was treated with DIPEA (0.056 mL, 0.033 mmol) and TBTU (0.065 g, 0.200 mmol). The mixture was then treated with benzylamine (0.015 mL, 0.011 mmol). The reaction was stirred at room temperature for 1 h. The reaction was diluted with water and the resulting precipitate was collected by filtration to afford the title compound (0.045 mg, 77% yield) as a pale yellow solid.

Provenance & Evidence