Water → HCID 86701845, compound

Participants

Reaction Steps

To a solution of ethyl 2-methyl-9-(methylsulfanyl)-2,4,5,6-tetrahydropyrazolo[4′,3′:6,7]cyclohepta[1,2-d]pyrimidine-3-carboxylate (100 mg, 0.31 mmol) in DMF (15 mL), oxone (580 mg, 0.94 mmol) was added. The mixture was stirred at room temperature overnight then water and AcOEt was added and the layers separated. The organic phase was finally dried over Na2SO4 and evaporated. The residue was triturated with Et2O and collected by filtration to give 105 mg (97% yield) of the title compound.

Provenance & Evidence