Glycine → Glycine, N-[[4-hydroxy-6-(phenylthio)-3-isoquinolinyl]carbonyl]-

Participants

Reaction Steps

127 mg of 4-hydroxy-6-phenylsulfanyl-isoquinoline-3-carboxylic acid butyl ester (0.36 mmol) were reacted with glycine and sodium methylate analogously to Example D-1 g). 118 mg of the title compound were obtained; 1H NMR (DMSO-d6): δ=9.33 (t, 1 H), 8.80 (s, 1 H), 8.11 (d, 1 H), 7.79 (s, 1 H), 7.49 to 7.65 (m, 6 H), 4.01 (d, 2 H).

Provenance & Evidence