Glycine → HCID 86014531, compound

Participants

Reaction Steps

216 mg of 1-bromo-4-hydroxy-6-phenylsulfanyl-isoquinoline-3-carboxylic acid butyl ester (0.5 mmol) from Example D-2a) were reacted with glycine and sodium methylate analogously to Example D-1 g). 194 mg of the title compound were obtained; 1H NMR (DMSO-d6): δ=9.17 (t, 1 H), 8.12 (d, 1 H), 7.51 to 7.78 (m, 7 H), 4.00 (d, 2 H).

Provenance & Evidence