Hydrochloric Acid → HCID 54588488, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-[4-(6-amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl]ethoxy}pyridin-3-yl)-3-methyl-1H-pyrazol-1-yl]piperidine-1-carboxylate (86 mg) in MeOH (1 mL) was added HCl (4N in dioxane, 0.73 mL). The mixture was stirred at RT for 1 hr. The mixture was concentrated and the residue purified by reverse phase prep-HPLC. The desired fractions were lyophillized to give the title compound (46 mg)

Provenance & Evidence