Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Fluoro-2,6-dimethylbenzaldehyde | HCID 40423753 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 85995662 | HCID 85995662 | — |
Reaction Steps
2.3 g (25 mmol) of phenol and 3.8 g (25 mmol) of 2,6-dimethyl-4-fluorobenzaldehyde were dissolved in 60 ml DMA, combined with 4.8 g (35 mmol) of K2CO3 and stirred at 150° C. for 5 min in a microwave (OEM Discoverer), filtered through basic Alox, washed with DMF and concentrated by rotary evaporation. Taken up in a mixture of acetonitrile/water. The substance crystallised, was filtered off and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08916589B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-4fb3bdc711b94d2d8cc7d46d36d91e25 |
|---|
| Source note | uspto-grants-2014_12 |
|---|
