反应详情

温度

50 °C

78 mg (0.32 mmol) of 1-[4-(4-methoxy-phenoxy)-phenyl]-ethanone were dissolved in 10 ml of 7M methanolic ammonia and combined with 50 mg of Raney nickel. The mixture was shaken for 6 h at 50° C. and 3 bar hydrogen pressure. Raney nickel was added twice more and hydrogenation was continued for 2 h and 6 h under the same conditions. The catalyst was removed by suction filtering and the residue was evaporated down.

1. waithydrogenation was continued for 2 h and 6 h under the same conditions
2. customThe catalyst was removed by suction
3. filtrationfiltering
4. customthe residue was evaporated down